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Creatine HSC
By now, we all know that creatine monohydrate is an extremely effective supplement. When you use
creatine, you get bigger and you get stronger. You can knock out more and more reps with heavier and heavier weights.
AST Sports Science's Creatine HSC takes the science of creatine supplementation to the next level. Creatine HSC is designed to create a more efficient and congruent atmosphere to increase creatine uptake and utilization within the muscle cell by effectively manipulating the intricate metabolic pathways of the phospho-creatine cycle.
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Now and Earn Club Credit!
Here's my current pre-workout and post-workout VP2 Whey Protein Isolate and Creatine HSC supplement strategy:
Pre-Workout - 4AM
2 scoops of VP2 Whey Protein Isolate; 1 scoop of
Creatine HSC.
Post-Workout - 5:15AM
2 scoops of VP2 Whey Protein Isolate; 1 scoop of
Creatine HSC.
I surround my intense, heavy morning weight training sessions with VP2 and Creatine
HSC. The VP2 before my workouts insures that I keep my muscles in a positive protein state while the carbohydrates in the Creatine HSC provide me with a good source of sustained energy to fuel my training sessions.
Right after my workouts, the high-quality protein in the VP2 and carbohydrates in the Creatine HSC start the critical muscle recovery process. These two key supplements immediately start repairing the muscle tissue damage I caused by overloading the muscles with heavy weight.
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Product
Highlights
• Increase Muscle Energy
• Increase Muscle Strength
• Increase Endurance
• Muscle Cell Hyper-Saturation
• Increase Creatine Uptake
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Creatine
HSC
While all the other companies are cutting corners to try and see just how cheap
they can sell you creatine, AST Sports Science is networking with leading
research groups around the world to deliver you state-of-the-art creatine
compounds that are more effective, work better and produce results that the
cheap creatine supplements can't come close to. Enter Creatine HSC!
"How to Pump Over 87%
More Muscle Building Creatine into Your Muscles... and Bio-Energetically Fuel
the Phospho-Creatine Cycle for Sustained and Continual Muscle Growth Over 247%
Greater Than Creatine Monohydrate!"
The Problem
We all know creatine monohydrate works! You take it -
you get bigger and you get stronger. You feel good, you feel big, and you feel
strong. You can knock out more and more reps with heavier and heavier weights.
It’s great stuff - at least for the first month or so. Then what happens? Bam!
You hit that wall. The weights aren’t moving up like they did at first. That
pump just doesn’t seem quite as full as it use to. You know what I mean. This
is called diminished creatine efficacy. It happens to everyone who relies on
simple creatine monohydrate for the their creatine saturation needs.
The Solution
One of the fundamental missions at AST Sports Science is
to foster a greater understanding into the dynamics of muscle anabolism through
nutritional intervention. With this fundamental approach AST Sports Science
became the first company to enhance the effectiveness of creatine monohydrate
with our original Creatine Complex-5™. Now Creatine HSC™ takes the science
of creatine supplementation even further. New Creatine HSC is designed to create
a more efficient and congruent atmosphere to increase creatine uptake and
utilization within the muscle cell by effectively manipulating the intricate
metabolic pathways of the phospho-creatine cycle.
Creatine HSC’s scientifically based creatine formula utilizes an advanced
substrate understanding to enhance the biological mechanisms of creatine
metabolism. Creatine HSC maximizes the integration of creatine carrier
sub-pathways and bioenergetic mediation to effectively increase muscle cell
creatine uptake, retention and creatine/ATP turnover.
Creatine HSC’s innovative “Hyper-Saturation Creatine Complex” incorporates
pure HPLC creatine monohydrate with an integrated bio-energetic ATP support
system, a dual-phosphate / taurine matrix, unique sodium / creatine mediators
and DGC™ (high-glycemic-index dextrorotatory glucose crystals) to help
facilitate a desired creatine “Hyper-Saturation” effect. Through this
“Hyper-Saturation” effect, Creatine HSC delivers over 87% more creatine to
your muscles than creatine monohydrate alone. And it doesn’t stop there...
Integrated ATP Support System
ATP Support System - AST Sports Science is currently the
only company researching the bio-energetic complexities of the phospho-creatine
cycle in order to gain a better understanding of the co-interactions with
relation to creatine / ATP synthesis. These important intermediaries are key to
increasing the intensity and duration of creatine’s muscle building effects.
By providing these essential intermediate substrates, Creatine HSC fuels a
micro-cellular environment prime for continued creatine/ATP turnover long after
other creatine supplements have stopped producing results. Other creatine
formulas ignore important substrate activity that is involved in the
proliferation of ATP.
This oversight limits creatine’s potential as a fuel and a buffer for ATP and
as a contributor to cell hyper-hydration, protein accrual and muscular growth.
Creatine HSC provides the necessary micro-nutrients that take advantage of
creatine’s site-specific substrate activity. By providing these bio-energetic
nutrients responsible for sustained creatine/ATP turnover, Creatine HSC delivers
continual dynamic muscle performance increases month after month after month.
Sodium-Creatine
Mediators
Sodium-Creatine Mediators - Unknown to but a few resourceful researchers,
creatine uptake by the muscle cell is sodium dependent - sodium is required for
proper muscle-creatine delivery and utilization. Providing the proper intra /
extra-cellular creatine-sodium chemical gradient is crucial to “hyper”
creatine transport - getting more creatine in the muscle than normally allowed
under ordinary cellular-metabolic states. Creatine HSC stimulates sodium-creatine
cotransport by increasing the transmembrane sodium concentration gradient. This
increased sodium flow into the cell allows a thermodynamic creatine attatchment
to “hitch-a-ride” in with the sodium. Creatine HSC provides a precise sodium
requirement to increase cellular creatine accumulation through cross-membrane
sodium transport. Another first in the industry.
Dual-Phosphate/Taurine Matrix
Dual-Phosphate / Taurine Matrix - Creatine HSC
integrates a precise sodium-potassium phosphate combination along with HPLC
Taurine for increased muscle cell hydration and insulin-like mediation for
creatine transport to promote an optimum cellular medium for accelerated muscle
growth. Controlled studies have demonstrated Taurine’s potent insulin-like
characteristics and have also shown insulin potentiating attributes as well.
This dual mimic-potentiate ability may foster an even greater net effect in
insulin mediated creatine transport. Numerous studies are indicating the more
creatine that can be driven into the muscle cell, the more potential for
substantial lean mass accumulation.
Spiking Insulin!
DGC™ - Creatine HSC incorporates new high-glycemic-index
dextrorotatory glucose crystals. This new glucose component helps mediate a
significant increase in creatine uptake and retention by having a sharp impact
on serum insulin levels. This insulin “spike” mediates a “hyper” uptake
of creatine into the muscle cell. DGC provides this insulin medium without the
overly sweet sensation other insulin spiking methods produce. Not only does
Creatine HSC redefine the science of creatine supplementation, but it now
provides a refreshing way to do it.
Two Muscle-Quenching Flavors!
New
Creatine HSC comes in two awesome and refreshing flavors - Juicy Grape and Lemon
Squeeze. Both are available in 2.2 pound (23 servings) and 4 pound (41 servings)
containers. You just scoop it into a glass, add cold water and stir. Creatine
HSC mixes instantly into a great tasting, very refreshing and potent
muscle-building drink. It doesn’t load you down or weigh heavy on your
stomach. Creatine HSC is simple to use and very effective.
Creatine HSC is a breakthrough supplement with a unique precision
“Hyper-Saturation" formula that integrates the absolute latest in
creatine research, delivering you the most scientifically advanced creatine
formula available to help you build lean muscle and strength faster. Creatine
HSC is defining a new era in creatine effectiveness. Creatine HSC will change
the way you think about fast muscle growth!
Order
Now and Earn Club Credit!
References:
1. Carbohydrate ingestion
augments skeletal muscle creatine accumulation during creatine supplementation
in humans. Am J Physiol 1996 Nov;271(5 Pt 1): E821-E826
2. Carbohydrate ingestion augments creatine retention during creatine feeding in
humans. Acct Physiol Scand 1996 Oct;158(2): 195-202
3. The utilization of creatine and its analogues by cytosolic and mitochondrial
creatine kinase. Biochim Biophys Acct 1996 Jun 13;1274(3):119-128
4. On the possible pharmacological role of UDP-glucose on some muscular
metabolites. Farmaco [Sci] 1984 Mar;39(3):246-254
5. Regulation of Ca2+ transport by insulin and taurine. Interaction at the level
of the Na(+)-Ca2+ exchanger. Adv Exp Med Biol. 1996 Jan 1; 403: 551-560
6. Interstitial fluid concentrations of glycerol, glucose, and amino acids in
human quadricep muscle and adipose tissue. Evidence for significant lipolysis in
skeletal muscle. J Clin Invest. 1995 Jul 1; 96(1): 370-377
7. Plasma and platelet taurine are reduced in subjects with insulin-dependent
diabetes mellitus: effects of taurine supplementation. Am J Clin Nutr. 1995 May
1; 61(5): 1115-1119
8. Does taurine bind to the insulin binding site of the insulin receptor? Prog
Clin Biol Res. 1990 Jan 1; 351: 95-102
9. Insulin-like activity of taurine. Adv Exp Med Biol. 1987 Jan 1; 217: 217-226
10. Potentiation of the actions of insulin by taurine. Can J Physiol Pharmacol.
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11. Stimulation of muscle protein synthesis by long-term insulin infusion in
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12. Physiologic hyperinsulinemia stimulates protein synthesis and enhances
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13. Glucose and amino acid transport in human peripheral lymphocytes. Biochem
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15. Regulation by insulin of muscle protein metabolism during sepsis and other
catabolic conditions. Nutrition. 1992 Nov 1; 8(6): 434-439
16. Characterization of the adenosine receptor modulating insulin action in rat
skeletal muscle. Eur J Pharmacol. 1992 Jun 5; 226(2): 121-128
17. Effect of insulin on protein synthesis and degradation in skeletal muscle
after exercise. Am J Physiol. 1990 Jan 1; 258(1 Pt 1): E92-E97 Am J Physiol.
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18. Effect of hormonal and substrate backgrounds on cell membrane function in
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Sep 1; 63(3): 1107-1113
19. A transient increase in amino acid transport modulated by insulin in
differentiating muscle cells. J Cell Physiol. 1979 Feb 1; 98(2): 279-282
20. Signaling elements involved in amino acid transport responses to altered
muscle cell volume. FASEB J. 1997 Nov; 11(13): 1111-1117
21. Effects of insulin and exercise on amino acid transport in rat skeletal
muscle. Am J Physiol. 1994 Feb 1; 266(2 Pt 1): C524-C530
22. A multichannel transporter for glucose and amino acid transport. Fiziol Zh
SSSR Im I M Sechenova. 1992 Aug 1; 78(8): 84-92
23. Amino acid transport System L in muscle cells: biochemical properties and
its relation to protein synthesis. Biochim Biophys Acta. 1992 Jul 8; 1108(1):
1-7
24. The regulation of total creatine content in a myoblast cell line. Mol Cell
Biochem. 1996 May 24; 158(2): 179-188
25. The cloning and expression of a human creatine transporter. Biochem Biophys
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influence of uraemia and inhibition of Na,K-ATPase. Cell Biochem Funct. 1994 Jun
1; 12(2): 99-106
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